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The required textbook for this course is: Lodish, et al. Molecular Cell Biology. 5th ed. New York, NY: W.H. Freeman and Company, 2003. ISBN: 9780716743668.
Course readings.
| SES # |
TOPICS |
READINGS |
| L1 |
Road map of course, what is and what is not cell biology, properties and behaviors of cells |
pp. 86-97, 184-193, and 235-239 |
| L2 |
Structure of biological membranes, lipids and lipid modification, membrane proteins |
pp. 43-46, 147-152, 157-165, 182-184, 245-257, and 260-270 |
| L3 |
Pumps, channels, transporters |
pp. 271-276 |
| L4 |
Receptors, basics of signal transduction (Note: Reprise and extension in lecture 14) |
pp. 82-86, 533-556, 561-567, and 571-598 |
| L5 |
Protein secretion, biogenesis of membrane proteins |
pp. 657-672 and 678-680 |
| E1 |
Exam I (lectures 1-5) |
|
| L6 |
Regulation of the cell division cycle |
pp. 853-863 and 881-886 |
| L7 |
Regulation of DNA replication |
pp. 874-881 |
| L8 |
The microtubule cytoskeleton |
pp. 817-827 and 838-848 |
| L9 |
Regulation of mitosis |
pp. 864-874 |
| L10 |
Meiosis |
pp. 890-894 |
| L11 |
Cell cycle checkpoints |
pp. 886-890 |
| E2 |
Exam II (lectures 6-11) |
|
| L12 |
Protein modifications and intracellular transport, glycosylation, vesicular transport, receptor mediated endocytosis, lysosomes, organelle biogenesis |
pp. 165-173, 438-443, 509-513, 673-696, and 701-732 |
| L13 |
Protein modifications and intracellular transport II |
pp. 165-173, 438-443, 509-513, 673-696, and 701-732 |
| L14 |
Signal transduction: Detailed molecular mechanisms |
pp. 482-484 and 639-644 |
| L15 |
Nerve cells, ion channels, synapse, Ca++ regulated events |
pp. 276-287 |
| L16 |
Nerve cells II |
pp. 287-296 and 735-739 |
| L17 |
Immunity and host pathogen interactions I |
Chapter 26, 6th ed. Provided as handout |
| L18 |
Immunity and host pathogen interactions II |
Chapter 26, 6th ed. Provided as handout |
| E3 |
Exam III (lectures 12-18) |
|
| L19 |
The actin-myosin cytoskeleton |
pp. 779-782, 784-786, 789-794, and 796-800 |
| L20 |
The extracellular matrix |
pp. 197-209, 223-227, 229-231, and 236-237 |
| L21 |
Cancer I |
pp. 935-950 |
| L22 |
Cancer II |
pp. 951-961, 965-970, and 884-885 |
| L23 |
Stem cells and cloning |
pp. 899-909 |
| E4 |
Exam IV (lectures 19-23) |
|